Phase angle cutoff value as a marker of the health status and functional capacity in breast cancer survivors

Accurate predictive tools are key factors for cancer care. Phase angle (PhA) has been proposed as a marker of cellular health, particularly cell-membrane integrity. Cutoff values have proposed, including survivors. This study aimed to assess the usefulness PhA cutoff, bioelectrical impedance analysis (BIA) assessed health-status, and functional capacity in breast (BC) cross-sectional included 25 women (50.6 ± 8.6 yrs) survivors BC, divided into two groups according reference value 5.6° (group 1 [G1]: ≤ [n=13]; group 2 [G2]: > [n=12]) (Gupta et al. 2008). BIA-assessed health status parameters included: extracellular water (ECW), intracellular (ICW), total body (TBW), PhA, mass, fat-free muscle cell mass (BCM). Four tests were performed: 30 s chair-stand test, timed up go ball throw test 6-minute walking test. Results showed G2 had lower ECW/ICW ratio (p=0.001; ES=1.2), ECW/BCM ES=3.2) ECW/TBW ES=4.8). There was no difference between groups. The results present show that patients with higher ICW preservation ratio, suggesting it's better membrane quality Relation both integrity warrants further research.